Publications

* 2) Stephanie Blachon, Xuyu Cai, Kela A Roberts, Kevin Yang, andrey Polyanovsky, Allen church, and Tomer Avidor-Reiss (2009). A Proximal Centriole-Like Structure is Present in Drosophila Spermatids and can serve as a model to study centriole duplication. Genetics, 2009 Mar 16. [Epub ahead of print] For abstract and PubMed link click here

Figure Art legend: Testis and PCL as a Model for Centriole Duplication
Center, combined DIC and a projection from a confocal picture of a complete fly testis labeled with Ana1-gfp labeling of centrioles and basal bodies.  The centriole size, shape and organization relative to each other change as the stem cells found at the tip of the testis (upper top) differentiate into a sperm cells (center of the figure).
On the corners, different stages of spermatids development showing the basal body and appearance of PCL at later stages (green) sitting below the nucleus (blue, DAPI) that differentiated from circular to elongated. Red mark a-tubulin.

1) Blachon S, Gopalakrishnan J, Omori Y, Polyanovsky A, Church A, Nicastro D, Malicki J, Avidor-Reiss T (2008). Drosophila Asterless the Ortholog of Vertebrate Cep152 is Essential for Centriole Duplication. Genetics,  Dec;180(4):2081-94. Epub 2008 Oct 14. For abstract and Pubmed link click here

Figure Art legend:while normal fly able clime a centriole; an aslmecD mutant fly is unable to stand on its legs because it has no centrioles

Avidor-Reiss T, Maer AM, Koundakjian E, Polyanovsky A, Keil T, Subramaniam S, Zuker CS (2004). Decoding cilia function: defining specialized genes required for compartmentalized cilia biogenesis. Cell , 117, 527-39. For abstract and PubMed link click here

* This study is recomended by Faculty of 1000 Biology